Th1 diseases are characterized by a strong Th1 response, while Th2 diseases are characterized by a weak or absent Th1 response Th1 cytokines like IFNγ and TNFα
The differentiation of Th1 and Th2 cells is regulated by many factors, and cytokines play the most important role Cytokines regulating Th2 cell differentiation Th1 cells are involved in the pathogenesis of organ-specific autoimmune disorders, Crohn's disease, Helicobacter pylori-induced peptic ulcer, acute kidney
pgasia88 In this review, we discuss the limitation of current Th1 cytokines as surrogates of protection and address the potential elements that should be considered Continuous presence of T-bet in differentiated TH1 cells was essential to ensure TH1 cell stability Thus, innate cytokine signals regulate TH1